What is the nanoscope and how it was developed

Published on Author Mario Greene

As far as nanoscope is concerned, it is considered as inescapable part of our modern life. The life would not the same after its invention, so it is worth to look how they were created, from simple microscopes to up-to-date nanoscopes.

Since the time when Dutch naturalist Antonie Philips van Leeuwehoek have seen the first small objects through his lens and understood that there is another sort of life there, it is impossible to imagine today the life without a microscope. Leeuwehoek could observe amoebae, ciliates, rotifers, bacteria, microscopic algae and different others tiny creatures all day long. The time has passed and many other researches and scientists began to use optical microscope in order to see clearly objects as small as micron. However, Ivanovsky had opened a tobacco mosaic virus at the end of XIX century, so it turned out that this “enemy” cannot be seen with an optical microscope. The problem is that the viruses like that are really common and cause the vast majority of diseases, so the need came up to create a tool that could show the objects in size of nanometers.

At the begging of XX century, the situation has changed a bit because of electron microscope. It triggered desired interest into biology as new science and suggested a golden opportunity to see viruses and cellular organelles. In addition, an electron microscope has one serious drawback: the flow of electrons used in it, instantly killing all living organisms that are investigated. Nevertheless, there is no need to kill them because it does not give insight of their actions and behavior. This problem was successfully solved by group of British-Singaporean scientists at Manchester University in 2011.

manchester university

First of all, they have created a nanoscope, which provides the opportunity to observe the live cells without killing them. At the same time, the principle of its functioning is fundamentally new. It includes sphere, which made of transparent quartz flogged, that helps to get the clear picture. Once you got it, the image could be obtained with the microlenses. The result is that such method of using nanoscope allows seeing the objects whose size is 50 nanometers. By the way, that’s 20 times faster than a conventional optical microscope. Furthermore, the head of research Lean Li stated that nanoscope is in its developing and they will advance it with ability to see the smaller objects over the time. Although, not only viruses and cell organelles are going to be studied, but also Blu-ray discs as well as anodized aluminum oxide nanostructures with the help of nanoscopes.

Finally, nanoscopes have played today the important role in science. Many companies started to use them for different purposes, not only for healthcare. One of those in UK is prominent nanoscope services company – LIG Technologies. LIG nanoscopes are used for viewing at live viruses and cells with the help of direct and quick observation and considered to be one of the best choices in the market.